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Ingredients
Black Cumin, Cumin
Black cumin, also known as Nigella sativa, has been shown to improve memory and focus in a number of studies:
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Memory
A study found that men in their 50s who took black cumin capsules for nine weeks performed better on memory, attention, and cognition tests than those who took a placebo.
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Executive functions
In elderly humans, taking black cumin capsules for nine weeks improved executive functions in memory tests.
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Spatial memory
In rats, black cumin seed improved spatial memory and recall.
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Neuroprotective
Black cumin oil has shown to preserve spatial cognitive functions in rats with chronic cerebral hypoperfusion, which is linked to Alzheimer's disease.
Black cumin's potential benefits for memory and focus are likely due to its antioxidant, anti-inflammatory, and neuron-protecting properties. Black cumin is a medicinal herb that's native to the eastern Mediterranean, northern Africa, southwest Asia, and the Indian subcontinent. It's also used in cooking.
Ginko biloba, Ginkgo
Ginkgo biloba is often used as a supplement to potentially improve memory and focus by enhancing blood circulation to the brain, acting as an antioxidant, and potentially protecting brain cells, though research on its effectiveness is mixed with some studies showing only modest improvements in cognitive function in healthy individuals, while others find no significant effect; it is not considered a reliable treatment for dementia or severe memory issues.
Key points about Ginkgo biloba and cognitive function:
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Potential benefits:
Some studies suggest that ginkgo may slightly improve memory, cognitive speed, and attention in healthy adults by enhancing blood flow to the brain.
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Mechanism:
Ginkgo contains flavonoids and terpenoids, which act as antioxidants and may help protect brain cells from damage.
Ilex paraquarinesis, Yerba Mate
Enhancing memory, mood, and alertness, Yerba Mate brings more motivation and stimulates the production of the neurotransmitter dopamine. It contains two compounds, theobromine and theophylline which are alkaloids working together with caffeine to provide a mild stimulant effect
Curcumin longa, Curcumin
Curcuma longa, also known as turmeric, may help with memory and focus in a number of ways:
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Improves memory
A UCLA study found that people who took curcumin improved their memory by 28% over 18 months.
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Reduces brain inflammation
Curcumin's antioxidant properties may reduce brain inflammation, which can lead to less decline in neurocognition.
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Improves interneuronal communication
Curcuma may improve communication between neurons in the hippocampus and PFC, which are regions of the brain involved in learning and memory.
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Preserves gut microbiota homeostasis
Curcumin may help prevent cognitive decline by preserving gut microbiota homeostasis.
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Reverses neurotoxic damage
Curcuma may reverse neurotoxic and behavioral damage in models of Alzheimer's disease.
Curcumin is the primary polyphenolic compound in turmeric, a spice that's often used in cooking.
Panax ginseng, Ginseng
Panax ginseng may improve memory and focus in some people, but the effects vary depending on the study and the participants:
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Healthy middle-aged people
Taking Panax ginseng by mouth may improve thinking, arithmetic skills, and reaction times.
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Healthy people between 38 and 66
Taking Panax ginseng with ginkgo leaf extract may improve memory.
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Healthy young adults
A single 400 mg dose of ginseng may improve cognitive performance, secondary memory performance, speed of performing memory tasks, and accuracy of attentional tasks.
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Healthy individuals
Taking 1 g/day of Panax ginseng for eight weeks may improve scores on executive function, attention, and memory.
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Elderly people in South Korea
Those who had higher lifetime cumulative ginseng intake showed higher cognitive scores compared to those who never consumed ginseng.
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Korean subjects with MCI
Taking ginseng orally for 6 months may have a positive effect on cognitive improvement, particularly on visual memory function.
Ginseng may also reduce inflammation, boost the immune system, and help treat erectile dysfunction.
Pau d'Arco, Maca
Maca root may help with memory and focus, and there is some evidence to support this:
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Animal studies
Some animal studies suggest that maca root can improve memory and learning, and slow cognitive decline in aging mice.
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Black maca
Clinical studies have shown that black maca may be the most effective type of maca for improving memory, learning, and brain clarity.
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Antioxidants
Maca root is high in antioxidants, which may be linked to improved memory.
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Native Peruvians
Native Peruvians are said to use maca root to help their children learn in school.
Other possible benefits of maca root include:
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Decreased delayed onset muscle soreness
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Improved bone health
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Skin benefits
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Wound healing
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Improved cardiovascular health
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Improved PCOS (polycystic ovary syndrome)
Non-Dairy Probiotic Cultures
Probiotics can help with memory and focus by improving gut health and the gut-brain connection:
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Gut health
Probiotics are beneficial bacteria and yeast that live in the gut and can help restore gut microbiota homeostasis. A healthy gut is important for normal cognitive processing.
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Gut-brain connection
The gut and brain communicate with each other through the gut-brain axis. Probiotics can help improve the gut-brain connection, which can lead to better memory and focus.
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Cognitive decline
Probiotics may help prevent or reverse some cognitive decline associated with aging. For example, one study found that participants with mild cognitive impairment who took the probiotic Lactobacillus rhamnosus GG (LGG) for three months saw improvements in their cognitive scores.
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Brain biochemical components
Probiotics can modify brain biochemical components like serotonin, dopamine, and γ-aminobutyric acid (GABA).
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Neurodegenerative disorders
Probiotics may be useful in treating neurodegenerative disorders like Alzheimer's disease or mild cognitive impairment.
However, not all randomized clinical trials have shown positive effects of probiotics on cognitive health. Factors that can influence the benefits of probiotics include the probiotic strain, dosage, duration of intervention, and disease severity
Blackberries, Blueberries, Raspberries and Strawberries
Berries may help with memory and focus in several ways:
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Improve blood flow
Berries contain flavonoids, which can increase blood flow and oxygen to the brain. This can help with concentration.
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Cross the blood-brain barrier
Flavonoids can cross the blood-brain barrier and accumulate in the hippocampus, which is the part of the brain associated with learning and memory.
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Reduce memory decline
Studies have shown that eating berries can slow memory decline in older adults. One study found that women who ate more berries had a delayed memory decline of up to two and a half years.
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Improve cognitive abilities
Berries may help with general cognitive abilities, learning, and memory.
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Reduce oxidative stress
The polyphenols in berries can help reduce and repair damage from oxidative stress, which can result from strenuous exercise.